Spotlight on Cognitive Function

Cognitive dysfunction is one of the hidden symptoms of MS.1 It can have a negative impact on a patient’s daily life, quality of life and employment.2,3 Symptoms commonly manifest as difficulty in information processing, concentration and attention, working memory and new learning.1,3


Monitoring the cognitive status of MS patients may enable the early detection of cognitive impairment, which could be particularly important in the early stages of MS as it can be a predictor for disease severity, and may also alter treatment plans.1
Unfortunately, cognitive function is rarely assessed during patients’ clinic visits due to the resource requirements and subtle nature of symptoms.3

Learn more about CogEval, a digital cognitive assessment tool.

Date of preparation: April 2021.

1. Bakirtzis C, Ioannidis P, Messinis L, et al. The rationale for monitoring cognitive function in multiple sclerosis: practical issues for clinicians. Review Open Neurol J. 2018;12:31-40.
2. Niccolai C, Goretti B, Amato MP. Disease modifying treatments and symptomatic drugs for cognitive impairment in multiple sclerosis: where do we stand? Mult Scler Demyelinating Disord. 2017; doi: 10.1186/s40893-017-0025-3. [Epub]
3. De Meijer L, Merlo D, Skibina O, et al. Monitoring cognitive change in multiple sclerosis using a computerized cognitive battery. Mult Scler J Exp Transl Clin. 2018; doi: 10.1177/2055217318815513. [Epub]